Protective effect of scorpion venom heat-resistant synthetic peptide against PM2.5-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway
Xin Xu, Henggui Xu, Fei Ren, Lanyi Huang, Jingbin Xu, Fasheng Li
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayNeuroprotectionProtein kinase BMicrogliaTLR4Cell biologyNF-κBSignal transductionPhosphorylationChemistryBiologyInflammationCancer researchPharmacologyBiochemistryImmunologyApoptosisAntimicrobial Peptides and ActivitiesNeuroinflammation and Neurodegeneration MechanismsExtracellular vesicles in disease