Membrane-Active Cyclic Amphiphilic Peptides: Broad-Spectrum Antibacterial Activity Alone and in Combination with Antibiotics
Eman H. M. Mohammed, Sandeep Lohan, Tarra Ghaffari, Shilpi Gupta, Rakesh Kumar Tiwari, Keykavous Parang
Abstract
for further development as a peptide-based antibiotic.
Topics & Concepts
ChemistryBroad spectrumAmphiphileAntibacterial activityAntibioticsCyclic peptideAntibacterial agentBiological activityCombinatorial chemistryMembraneBiochemistryBacteriaPeptideOrganic chemistryIn vitroCopolymerPolymerGeneticsBiologyAntimicrobial Peptides and ActivitiesChemical Synthesis and AnalysisAntimicrobial agents and applications