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Inhibition of Serum- and Glucocorticoid-Regulated Protein Kinase-1 Aggravates Imiquimod-Induced Psoriatic Dermatitis and Enhances Proinflammatory Cytokine Expression through the NF-kB Pathway

Qinqin Meng, Mei Bai, Meiliang Guo, Zhengxiao Li, Wanwen Liu, Xiaojing Fan, Rui Sun, Xin-Rong Yang, Yuan Ding-fen, Yuling Shi, Hui Deng

2023Journal of Investigative Dermatology18 citationsDOIOpen Access PDF

Topics & Concepts

Proinflammatory cytokineTyrosine kinasePsoriasisSGK1Bruton's tyrosine kinaseGlucocorticoid receptorCancer researchKinaseSignal transductionInflammationImmunologyMedicineBiologyGlucocorticoidCell biologyPsoriasis: Treatment and PathogenesisDermatology and Skin DiseasesPhytochemistry and Bioactive Compounds
Inhibition of Serum- and Glucocorticoid-Regulated Protein Kinase-1 Aggravates Imiquimod-Induced Psoriatic Dermatitis and Enhances Proinflammatory Cytokine Expression through the NF-kB Pathway | Litcius