Combined targeting of CCL7 and Flt3L to promote the expansion and infiltration of cDC1s in tumors enhances T-cell activation and anti-PD-1 therapy effectiveness in NSCLC
Hong‐Peng Dong, Ying Li, Zhen Tang, Peng Wang, Bo Zhong, Qian Chu, Dandan Lin
Topics & Concepts
Cancer researchInfiltration (HVAC)CCL7MedicinePharmacologyInternal medicineMaterials scienceReceptorChemokineComposite materialCXCL10Cancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmune Cell Function and Interaction