CSMD1 suppresses cancer progression by inhibiting proliferation, epithelial-mesenchymal transition, chemotherapy-resistance and inducing immunosuppression in esophageal squamous cell carcinoma
Xing Wang, Xinwei Chen, Yuanyuan Liu, Shan Huang, Jian Ding, Baoxin Wang, Dong Pin, Zhenfeng Sun, Lixiao Chen
Abstract
T cells expansion and activation, and could increase cytokines secretion, indicating that tumor cell-associated CSMD1 might be a target for ESCC.
Topics & Concepts
BiologyCancer researchTumor progressionCD8Cytotoxic T cellImmunologyCancerImmune systemIn vitroBiochemistryGeneticsCancer Immunotherapy and BiomarkersEpigenetics and DNA MethylationImmune cells in cancer