Gut-Lung Axis in COVID-19
Imane Allali, Youssef Bakri, Saaïd Amzazi, Hassan Ghazal
Abstract
COVID-19 is a pandemic infection of the respiratory system caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The viral ribonucleic acid (RNA) was found in many parts of the COVID-19 patients including the stool, suggesting a potential interaction with the host's gut microbiome. The gut microbiome also plays major roles in immunity and inflammation. It also impacts pulmonary functions through the gut-lung axis. There have been recent reports of the importance of the host microbiome in infection and pathogenicity. The understanding of the gut and lung microbiomes would open the gate to new therapeutic approaches.
Topics & Concepts
MicrobiomeLungCoronavirus disease 2019 (COVID-19)Gut microbiomeMedicineImmunologyImmunityRespiratory systemCoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Host (biology)PandemicVirologyBiologyImmune systemBioinformaticsPathologyInternal medicineDiseaseGeneticsInfectious disease (medical specialty)Gut microbiota and healthClostridium difficile and Clostridium perfringens researchDietary Effects on Health