Design, synthesis, and antitumor activity of novel compounds based on 1,2,4-triazolophthalazine scaffold: Apoptosis-inductive and PCAF-inhibitory effects
Abdallah Turky, Ashraf H. Bayoumi, Adel Ghiaty, Adel S. El‐Azab, Alaa A.‐M. Abdel‐Aziz, Hamada S. Abulkhair
Topics & Concepts
IC50ChemistryDoxorubicinAfatinibApoptosisPaclitaxelPharmacologyCancerBiochemistryIn vitroMedicineChemotherapyInternal medicineReceptorGefitinibEpidermal growth factor receptorCancer therapeutics and mechanismsQuinazolinone synthesis and applicationsSynthesis and biological activity