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Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA

Xinxing Lyu, Kai‐Hang Lei, Pau Biak Sang, Olga Shiva, Megan Chastain, Peter Chi, Weihang Chai

2020The EMBO Journal64 citationsDOIOpen Access PDF

Topics & Concepts

BiologyNucleaseCell biologyReplication protein ADNAGenome instabilityDNA replicationDNA-binding proteinDNA damageGeneticsMolecular biologyGeneTranscription factorDNA Repair MechanismsCRISPR and Genetic EngineeringGenomics and Chromatin Dynamics
Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA | Litcius