Litcius/Paper detail

Potential solutions for manufacture of CAR T cells in cancer immunotherapy

Ulrich Blache, Georg Popp, Anna Dünkel, Ulrike Koehl, Stephan Fricke

2022Nature Communications135 citationsDOIOpen Access PDF

Abstract

CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups.

Topics & Concepts

ImmunotherapyCancer immunotherapyCancer treatmentCancerCancer therapyMedicineInternal medicineCAR-T cell therapy researchNanowire Synthesis and ApplicationsViral Infectious Diseases and Gene Expression in Insects