Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice
Praveen Kumar Dubey, Mallikarjun Patil, Sarojini Singh, Shubham Dubey, Paras Ahuja, Suresh K Verma, Prasanna Krishnamurthy
Topics & Concepts
RNA methylationMethylationGene knockdownN6-MethyladenosineProinflammatory cytokineInflammationLipopolysaccharideDemethylaseRNADownregulation and upregulationTumor necrosis factor alphaCytokineGene expressionInternal medicineBiologySmall interfering RNAGene silencingEndocrinologyMethyltransferaseMedicineGeneEpigeneticsBiochemistryRNA modifications and cancerCardiac Structural Anomalies and RepairHVDC Systems and Fault Protection