Synthesis of Ni<sub>0.5</sub>Co<sub>0.5-x</sub>Cd<sub>x</sub>Fe<sub>1.78</sub>Nd<sub>0.02</sub>O<sub>4</sub> (x ≤ 0.25) nanofibers by using electrospinning technique induce anti-cancer and anti-bacterial activities
Fatimah Alahmari, Suriya Rehman, M.A. Almessiere, Firdos Alam Khan, Y. Slimani, A. Baykal
Abstract
Here we report the electrospinning synthesis of Cd-substituted Ni-Co ferrite Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x ≤ 0.25) nanofiber (NFs) with a very low concentration of Nd as a dopant. The structure and surface morphology of the Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x ≤ 0.25) NFs were analyzed by X-ray powder pattern (XRD), transmission and scanning electron microscopes (TEM) along with Energy-dispersive X-ray (EDX). We have examined the biological applications of the Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x ≤ 0.25) NFs on both cancerous cells and bacterial cells. We have found that Ni0.5Co0.5-xCdxFe1.78Nd0.02O4 (x ≤ 0.25) NFs produced inhibitory action on the human colorectal carcinoma cells (HEK-293) and also showed inhibitory action on the bacterial strains (S. aureus and E. coli) respectively. Finally, this is the first report on the synthesis of Cd- substituted Co–Ni ferrite nanofibers using electrospinning technique exhibiting anti-cancer and anti-bacterial activities.Communicated by Ramaswamy H. Sarma