Litcius/Paper detail

A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

Chenxi Xu, Fanye Meng, Kwang‐Su Park, Aaron J. Storey, Weida Gong, Yi‐Hsuan Tsai, Elisa Gibson, Stephanie D. Byrum, Dongxu Li, Rick D. Edmondson, Samuel G. Mackintosh, Masoud Vedadi, Ling Cai, Alan J. Tackett, H. Ümit Kanıskan, Jian Jin, Gang Greg Wang

2021Cell chemical biology62 citationsDOIOpen Access PDF

Topics & Concepts

Cancer researchCRISPRCell biologyPAS domainBiologyChemistryGeneGeneticsTranscription factorProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis