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Hypoxia Inducible Factor-1α (HIF-1α) Mediates NLRP3 Inflammasome-Dependent-Pyroptotic and Apoptotic Cell Death Following Ischemic Stroke

Qian Jiang, Xiaokun Geng, Jonathan R. Warren, Eric Cosky, Shawn Kaura, Christopher Stone, Fengwu Li, Yuchuan Ding

2020Neuroscience182 citationsDOI

Topics & Concepts

InflammasomeProgrammed cell deathApoptosisPyroptosisHypoxia (environmental)MedicineIschemiaReperfusion injuryHypoxia-inducible factorsStroke (engine)ImmunologyCell biologyInflammationChemistryBiologyInternal medicineBiochemistryOxygenGeneEngineeringOrganic chemistryMechanical engineeringInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxideinterferon and immune responses
Hypoxia Inducible Factor-1α (HIF-1α) Mediates NLRP3 Inflammasome-Dependent-Pyroptotic and Apoptotic Cell Death Following Ischemic Stroke | Litcius