Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors
Yanming Zhang, Shuang Ye, Yuan Wang, Chuanhao Wang, Yazhao Zhu, Yuelin Wu, Yongqiang Zhang, Huojun Zhang, Zhenyuan Miao
Topics & Concepts
Betulinic acidChemistryLead compoundPharmacologyImmunotherapyBiochemistryImmune systemIn vitroImmunologyBiologyGeneticsAdenosine and Purinergic SignalingPneumocystis jirovecii pneumonia detection and treatmentPeptidase Inhibition and Analysis