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Intermittent hypoxia inhibits anti-tumor immune response via regulating PD-L1 expression in lung cancer cells and tumor-associated macrophages

Zhilei Cui, Zhengshang Ruan, Meigui Li, Rongrong Ren, Yizong Ma, Junxiang Zeng, Jinyuan Sun, Wenjing Ye, Weiguo Xu, Xuejun Guo, Dengfei Xu, Linlin Zhang, Linlin Zhang

2023International Immunopharmacology26 citationsDOI

Topics & Concepts

Hypoxia (environmental)Lung cancerIntermittent hypoxiaDownregulation and upregulationImmune systemCancer researchTumor hypoxiaMedicineTumor progressionPD-L1LungAdenocarcinomaCancerImmunologyInternal medicineImmunotherapyBiologyObstructive sleep apneaChemistryGeneOrganic chemistryRadiation therapyOxygenBiochemistryCancer, Hypoxia, and MetabolismObstructive Sleep Apnea ResearchImmune cells in cancer
Intermittent hypoxia inhibits anti-tumor immune response via regulating PD-L1 expression in lung cancer cells and tumor-associated macrophages | Litcius