Ketoconazole-Loaded Cationic Nanoemulsion: <i>In Vitro</i>–<i>Ex Vivo</i>–<i>In Vivo</i> Evaluations to Control Cutaneous Fungal Infections
Mudassar Shahid, Afzal Hussain, Azmat Ali Khan, Mohhammad Ramzan, Ahmed L. Alaofi, Amer M. Alanazi, Mohammed M. Alanazi, Mohd Ahmar Rauf
Abstract
irritation studied confirmed the safety concern of the nanoemulsion at the explored composition. Long-term stability result revealed a stable product at the explored temperature for a year. Conclusively, cationic nanoemulsion is a promising approach to deliver KTZ for high permeation and therapeutic efficacy.
Topics & Concepts
In vivoKetoconazoleHemolysisEx vivoCandida albicansCandida tropicalisIn vitroPermeationChemistryCandida kruseiPharmacologyChromatographyMicrobiologyMedicineBiologyBiochemistryAntifungalImmunologyMembraneBiotechnologyNail Diseases and TreatmentsAdvancements in Transdermal Drug DeliveryContact Dermatitis and Allergies