A rapid liquid biopsy of lung cancer by separation and detection of exfoliated tumor cells from bronchoalveolar lavage fluid with a dual-layer “PERFECT” filter system
Tingyu Li, Yaoping Liu, Wei Zhang, Lianjun Lin, Jixin Zhang, Yan Xiong, Ligong Nie, Xinmin Liu, Haichao Li, Wei Wang
Abstract
: The easy and rapid processing of BALF samples with varying volume and turbidity, competitive sensitivity and good versatility for different lung cancer types will make the established dual-layer PERFECT filter system a promising approach for the liquid biopsy of BALF. The high-performance BALF-based liquid biopsy will improve the cytopathological identification and diagnosis of lung cancer.
Topics & Concepts
Bronchoalveolar lavageLung cancerLiquid biopsyBiopsyMedicineCancerLungPathologyInternal medicineCancer Cells and MetastasisCancer Genomics and DiagnosticsMedical Imaging and Pathology Studies