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Empirical Comparison and Analysis of Web-Based DNA N4-Methylcytosine Site Prediction Tools

Balachandran Manavalan, Md Mehedi Hasan, Shaherin Basith, Vijayakumar Gosu, Tae Hwan Shin, Gwang Lee

2020Molecular Therapy — Nucleic Acids46 citationsDOIOpen Access PDF

Abstract

, thereby limiting their practical applicability. Model transferability to five species and non-transferability to three species are also discussed. The presented evaluation will assist researchers in selecting appropriate prediction tools that best suit their purpose and provide useful guidelines for the development of improved 4mC predictors in the future.

Topics & Concepts

Identification (biology)Computer scienceComputational biologyGenomeTransferabilityMachine learningBiologyGeneticsEcologyLogitGeneEpigenetics and DNA MethylationMachine Learning in BioinformaticsGenomics and Phylogenetic Studies