Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors
Amine M. Laradji, Alexander V. Kolesnikov, Bedia Begüm Karakoçak, Vladimir J. Kefalov, Nathan Ravi
Abstract
untreated controls. To the best of our knowledge, this report constitutes the first attempt to use a topically applied triggered-release drug delivery system to target the pigmented layer of the retina, in addition to the first attempt to deliver the visual chromophore topically.
Topics & Concepts
RetinalRetinaHyaluronic acidChromophoreDrug deliveryChemistryBiophysicsMedicineNanotechnologyMaterials scienceNeuroscienceBiologyBiochemistryAnatomyPhotochemistryOcular Surface and Contact LensRetinal Development and DisordersPhotochromic and Fluorescence Chemistry