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A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors

Analía Azaro, Christophe Massard, William D. Tap, Philippe A. Cassier, Jaime R. Merchan, Antoîne Italiano, Bailey Anderson, Eunice Yuen, Danni Yu, Gerard J. Oakley, Karim A. Benhadji, Shubham Pant

2021Investigational New Drugs34 citationsDOI

Topics & Concepts

Notch signaling pathwayMedicineSolid tumorCancer researchPharmacologyCancerInternal medicineReceptorAdvanced Breast Cancer TherapiesNeuroendocrine Tumor Research AdvancesCancer Mechanisms and Therapy
A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors | Litcius