Isoxazole compounds: Unveiling the synthetic strategy, in-silico SAR & toxicity studies and future perspective as PARP inhibitor in cancer therapy
Udita Malik, Dilipkumar Pal
Topics & Concepts
ChemistryIn silicoPARP inhibitorIsoxazoleToxicityCancer therapyPerspective (graphical)PharmacologyCancerPoly ADP ribose polymeraseStereochemistryBiochemistryInternal medicinePolymeraseDNAOrganic chemistryArtificial intelligenceComputer scienceGeneMedicinePARP inhibition in cancer therapyCell death mechanisms and regulationCancer therapeutics and mechanisms