Access to <i>P</i>-stereogenic compounds <i>via</i> desymmetrizing enantioselective bromination
Qiuhong Huang, Qian-Yi Zhou, Chen Yang, Li Chen, Jin‐Pei Cheng, Xin Li
Abstract
A highly efficient desymmetrizing asymmetric bromination of bisphenol phosphine oxides was developed, providing a wide range of chiral bisphenol phosphine oxides and bisphenol phosphinates with high yields and enantioselectivities.
Topics & Concepts
StereocenterHalogenationBisphenol AEnantioselective synthesisPhosphineBisphenolBisphenol SChemistryOrganic chemistryCatalysisEpoxyAxial and Atropisomeric Chirality SynthesisAsymmetric Synthesis and CatalysisAsymmetric Hydrogenation and Catalysis