Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3
Xuejiao Leng, Jianfeng Wang, Na An, Xue Wang, Yile Sun, Zhiwei Chen
Topics & Concepts
DemethylaseH3K4me3Gene knockdownBiologyCarcinogenesisCancer researchEpigeneticsHistoneLung cancerCancerTranscription factorHistone methylationCell cultureGene expressionInternal medicineGeneGeneticsPromoterMedicineDNA methylationEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchCancer-related gene regulation