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Neuro-epithelial circuits promote sensory convergence and intestinal immunity

Wen Zhang, Elizabeth Emanuel, Hiroshi Yano, Jazib Uddin, Stephen Gaudino, ZiLi Xie, Hiroshi Ichise, Zhen Wang, Maureen N. Cowan, Mengze Lyu, Xiaoxiao Hou, Peng Zeng, Elin Hu, Victoria Ribeiro de Godoy, Alex Grier, Nina Estep, J Ishibashi, Stephanie Añover-Sombke, Peter J. Skene, Toufic Mayassi, Ramnik J. Xavier, Ronald N. Germain, Anna-Maria Globig, Maximilian Heeg, Ananda W. Goldrath, Brian Kim, Hongzhen Hu, David Artis

2026Nature11 citationsDOIOpen Access PDF

Topics & Concepts

TuftNociceptorCell biologyBiologyCell typeInflammationImmune systemCalcitonin gene-related peptideNeurogenic inflammationSensory systemReceptorImmunityCellImmunologyNeuroscienceInnate immune systemGene silencingSignal transductionEfferentIntestinal mucosaNeuropeptideAllergic inflammationPattern recognition receptorSensory neuronDendritic cellNeural crestPurinergic receptorBiochemical Analysis and Sensing TechniquesIon Channels and ReceptorsGastrointestinal motility and disorders
Neuro-epithelial circuits promote sensory convergence and intestinal immunity | Litcius