Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer
Ouxuan Liu, Caixia Wang, Shuang Wang, Yuexin Hu, Rui Gou, Hui Dong, Siting Li, Xiao Li, Bei Lin
Abstract
KRT80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer, and KRT80 may have applications as a screening biomarker and potential therapeutic target for ovarian cancer.
Topics & Concepts
Ovarian cancerCancer researchMAPK/ERK pathwayGene knockdownCancerBiologyTumor progressionEpithelial–mesenchymal transitionSignal transductionMedicineMetastasisInternal medicineCell cultureCell biologyGeneticsSkin and Cellular Biology ResearchReproductive Biology and FertilityHeat shock proteins research