Antibacterial activity of curcumin – a natural phenylpropanoid dimer from the rhizomes of <i>Curcuma longa L</i>. and its synergy with antibiotics

Abstract

Curcumin is a natural substance extracted from turmeric that has broad-spectrum antibacterial properties. The aim of the study was to assess the antibacterial activity of curcumin and its interactions with selected antibiotics against drug-sensitive and multidrug-resistant isolates of emerging bacterial pathogens frequently found in healthcare settings. Materials and method. Antibacterial activity of curcumin was assessed by MIC and MBC values against a total of 30 drugsensitive and drug-resistant bacterial strains. Curcumin synergy with antibiotics was identified by the checkerboard method.

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