Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein
Sara A. M. Holec, Jisoo Lee, Abby Oehler, Felicia K. Ooi, Daniel A. Mordes, Steven H. Olson, Stanley B. Prusiner, Amanda L. Woerman
Topics & Concepts
AtrophyNeurodegenerationNeuropathologyBiologyGenetically modified mouseWild typeAlpha-synucleinPathologyMolecular biologyTransgeneVirologyDiseaseParkinson's diseaseMedicineGeneticsGeneMutantParkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismNuclear Receptors and Signaling