Litcius/Paper detail

A reference scale of cucurbit[7]uril binding affinities

Mohammad A. Alnajjar, Werner M. Nau, Andreas Hennig

2021Organic & Biomolecular Chemistry42 citationsDOIOpen Access PDF

Abstract

The binding of the macrocyclic host cucurbit[7]uril with selected guest molecules has been re-investigated to cover a large range in affinities (millimolar to femtomolar) and to set up a reference scale for future binding constant determinations.

Topics & Concepts

AffinitiesBinding affinitiesChemistryScale (ratio)StereochemistryBiochemistryGeographyReceptorCartographySupramolecular Chemistry and ComplexesCrystallography and molecular interactionsAdvanced NMR Techniques and Applications