Expression and regulatory characteristics of peripheral blood immune cells in primary Sjögren’s syndrome patients using single-cell transcriptomic
Jinkun Liu, Hongyan Gao, Chengyin Li, Fenglin Zhu, Miao Wang, Yanqiu Xu, Bin Wu
Abstract
CD16+FCER1G- NK cells. Our analysis provides a reference dataset and reveals its immune heterogeneity among PBMCs in pSS.
Topics & Concepts
CD14CD16Peripheral blood mononuclear cellImmune systemMonocyteImmunologyTranscriptomeDownregulation and upregulationBiologyCellInnate immune systemTranscription factorGene expressionMedicineGeneGeneticsCD3CD8In vitroSalivary Gland Disorders and FunctionsSingle-cell and spatial transcriptomicsImmune Cell Function and Interaction