Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms
Michal P. Wandel, Bae-Hoon Kim, Eui‐Soon Park, Keith B. Boyle, Komal Nayak, Brice Lagrange, Adrian Herod, Thomas Henry, Matthias Zilbauer, John R. Rohde, John D. MacMicking, Felix Randow
Topics & Concepts
PyroptosisCell biologyShigella flexneriCytosolCaspaseBiologyIntracellular parasiteInflammasomeIntracellularSignal transductionProgrammed cell deathApoptosisBiochemistryEscherichia coliReceptorEnzymeGeneInflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation