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Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis

Yuyin Pan, Junmei Lü, Xinran Feng, Shengyi Lu, Yi Yang, Guang Yang, Shudan Tan, Liang Wang, Pilong Li, Shouqing Luo, Boxun Lu

2023Nature Chemical Biology21 citationsDOI

Topics & Concepts

RNAProtein biosynthesisTranslation (biology)CytoplasmNeurodegenerationCell biologyBiologyTrinucleotide repeat expansionChemistryMolecular biologyMessenger RNABiochemistryGeneDiseaseMedicinePathologyAlleleGenetic Neurodegenerative DiseasesRNA Research and SplicingMitochondrial Function and Pathology
Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis | Litcius