Circular RNA Arhgap12 modulates doxorubicin-induced cardiotoxicity by sponging miR-135a-5p
Xuejun Wang, Zijie Cheng, Jia Xu, Mengwen Feng, Hao Zhang, Li Zhang, Lingmei Qian
Topics & Concepts
CardiotoxicityDownregulation and upregulationApoptosisDoxorubicinMolecular biologymicroRNATerminal deoxynucleotidyl transferaseReactive oxygen speciesCircular RNAMessenger RNAChemistryReporter geneSuperoxide dismutaseCompeting endogenous RNALuciferaseBiologyOxidative stressCell biologyTransfectionGene expressionTUNEL assayGeneBiochemistryToxicityLong non-coding RNAChemotherapyOrganic chemistryGeneticsCircular RNAs in diseasesChemotherapy-induced cardiotoxicity and mitigationGDF15 and Related Biomarkers