Slug enables redox-sensitive trans-activation of LRP1 by COUP-TFII: Implication in antifibrotic intervention in the kidneys
Xiaoyan Wu, Xiulian Miao, Yan Guo, Tinghui Shao, Shifan Tang, Yanshan Lin, Yong Xu, Nan Li, Tao Zhang
Topics & Concepts
Gene knockdownLRP1MyofibroblastFibrosisKidneyTranscription factorCancer researchCell biologySlugNuclear receptorBiologyChemistryInternal medicineEndocrinologyMedicineGeneBiochemistryLDL receptorLipoproteinCholesterolChronic Kidney Disease and DiabetesDialysis and Renal Disease ManagementNeutrophil, Myeloperoxidase and Oxidative Mechanisms