Organobase 1,1,3,3-tetramethyl guanidine catalyzed rapid ring-opening polymerization of α-amino acid <i>N</i>-carboxyanhydrides adaptive to amine, alcohol and carboxyl acid initiators
Kai Li, Zheng Li, Zheng Li, Yong Shen, Xiaohui Fu, Chongyi Chen, Zhibo Li, Zhibo Li
Abstract
For amine, hydroxyl and carboxyl terminated initiators, the organobase 1,1,3,3-tetramethylguanidine (TMG) catalyzes the rapid polymerization to afford polypeptides with controllable molecular weights and dispersities.
Topics & Concepts
ChemistryGuanidineAmine gas treatingPolymerizationPolymer chemistryCatalysisRing-opening polymerizationAlcoholAmino acidRing (chemistry)Organic chemistryPolymerBiochemistrybiodegradable polymer synthesis and propertiesClick Chemistry and ApplicationsAdvanced Polymer Synthesis and Characterization