Design, synthesis, molecular docking and anticancer evaluations of 5-benzylidenethiazolidine-2,4-dione derivatives targeting VEGFR-2 enzyme
Khaled El‐Adl, Abdel‐Ghany A. El‐Helby, Helmy Sakr, Ibrahim H. Eissa, Sanadelaslam S. A. El‐Hddad, Fatma M.I.A. Shoman
Topics & Concepts
ChemistrySorafenibIC50StereochemistryDocking (animal)DoxorubicinCell cultureLead compoundEnzymeDerivative (finance)In vitroBiochemistryCancer researchGeneticsHepatocellular carcinomaFinancial economicsSurgeryEconomicsBiologyMedicineChemotherapyNursingSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactions of Organic Compounds