Emergence of a Novel Plasmid-Mediated Tigecycline Resistance Gene Cluster, <i>tmexCD4-toprJ4</i> , in Klebsiella quasipneumoniae and Enterobacter <i>roggenkampii</i>
Xun Gao, Cheng-Zhen Wang, Luchao Lv, Xiaotong He, Zhongpeng Cai, Wan-Yun He, Tong Li, Jian–Hua Liu
Abstract
, suggesting that this gene cluster is already present in the human-associated environment and the risk of transmission to humans is increased. Monitoring tigecycline-resistant Gram-negative bacteria is essential for understanding and addressing the spread of this gene cluster in agriculture and health care.
Topics & Concepts
TigecyclinePlasmidBiologyGene clusterGeneGeneticsMicrobiologyEnterobacterAntibioticsEscherichia coliAntibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental ImpactsBacterial Genetics and Biotechnology