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Employing Visible-Light Photoredox Catalysis in Multicomponent–Multicatalyst Reactions: One-Pot Synthesis of Spiroquinazolin-2-(thi)ones

Zhentao Pan, Xuancheng Yang, Bo Chen, Shuaijun Shi, Tong Liu, Xu‐Qiong Xiao, Linlin Shen, Lou Li, Yongmin Ma

2022The Journal of Organic Chemistry21 citationsDOI

Abstract

The multicomponent–multicatalyst reaction ((MC)2R) and visible-light catalysis have emerged as green and powerful strategies for achieving ideal syntheses. Here, we report the first example of a visible-light-induced approach toward spiroquinazolin(thi)ones. This (MC)2R features an eco-friendly energy source and solvent, metal-free catalysts, step- and atom-economy, a relay catalysis strategy, air as green oxidant, mild conditions, and easily accessible starting materials.

Topics & Concepts

CatalysisPhotoredox catalysisVisible spectrumAtom economyEnvironmentally friendlyPhotochemistryChemistryGreen-lightIdeal (ethics)SolventAtom (system on chip)Green chemistryLight sourceCombinatorial chemistryNanotechnologyMaterials sciencePhotocatalysisOrganic chemistryReaction mechanismComputer scienceOptoelectronicsPhysicsBlue lightOpticsEmbedded systemBiologyPhilosophyEpistemologyEcologyRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods
Employing Visible-Light Photoredox Catalysis in Multicomponent–Multicatalyst Reactions: One-Pot Synthesis of Spiroquinazolin-2-(thi)ones | Litcius