Engineering Large‐Scale Self‐Mineralizing Bone Organoids with Bone Matrix‐Inspired Hydroxyapatite Hybrid Bioinks (Adv. Mater. 30/2024)
Jian Wang, Yan Wu, Guangfeng Li, Fengjin Zhou, Xiang Wu, Miaomiao Wang, Xinru Liu, Hua Tang, Long Bai, Zhen Geng, Peiran Song, Zhongmin Shi, Xiaoxiang Ren, Jiacan Su
Abstract
Bone Organoids Bone organoids serve as innovative tools in biomedical research, enhancing our understanding of bone biology and related diseases. Current bone organoid research is still in its infancy. In article number 2309875, Jiacan Su and co-workers present a novel approach using bone matrix-inspired hydroxyapatite hybrid bioinks to fabricate large-scale self-mineralizing bone organoids via bioprinting. These miniature, self-organizing structures mimic the complexity of bone tissue.
Topics & Concepts
Materials scienceOrganoidMatrix (chemical analysis)Bone matrixBiomedical engineeringComposite materialAnatomyBiologyNeuroscienceEngineeringCartilage3D Printing in Biomedical Research