Supramolecular nanofiber of indomethacin derivative confers highly cyclooxygenase-2 (COX-2) selectivity and boosts anti-inflammatory efficacy
Deqing Lin, Xiaoning Xu, Lin Chen, Lei Chen, Mengyun Deng, Jinrun Chen, Zhibin Ren, Lei Lei, Jiaqing Wang, Jie Deng, Xingyi Li
Topics & Concepts
CyclooxygenaseProstaglandin-Endoperoxide SynthaseNanofiberSelectivityChemistryDerivative (finance)Supramolecular chemistryPharmacologyAnti-inflammatoryCombinatorial chemistryMedicineBiochemistryNanotechnologyMaterials scienceOrganic chemistryEnzymeMoleculeCatalysisEconomicsFinancial economicsInflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis of β-Lactam Compounds