A synthetic lethal approach to drug targeting of G-quadruplexes based on CX-5461
Meiyu Jin, Laurence H. Hurley, Hong Xu
Topics & Concepts
Synthetic lethalityEpigeneticsDNA repairGeneCancerDrugDrug discoveryHomologous recombinationBiologyGeneticsChemistryComputational biologyCancer researchBioinformaticsPharmacologyDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery