Litcius/Paper detail

CRISPR screens decode cancer cell pathways that trigger γδ T cell detection

Murad R. Mamedov, Shane Vedova, Jacob W. Freimer, Avinash Sahu, Amrita Ramesh, Maya M. Arce, Angelo D. Meringa, Mineto Ota, Peixin Amy Chen, Kristina Hanspers, Vinh Nguyen, Kirsten A. Takeshima, Anne C. Rios, Jonathan K. Pritchard, Jürgen Kuball, Zsolt Sebestyén, Erin J. Adams, Alexander Marson

2023Nature92 citationsDOIOpen Access PDF

Topics & Concepts

AMPKCell biologyCRISPRCellCancer cellBiologySignal transductionCell cultureProtein kinase AEffectorT cellDownregulation and upregulationChemistryCancerGeneKinaseGeneticsImmune systemImmune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy research