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Recruitment of FBXO22 for targeted degradation of NSD2

Yan Nie, John R. Tabor, Jianping Li, Maria Kutera, Jonathan St‐Germain, Ronan P. Hanley, Esther Wolf, Ethan Paulаkonis, Tristan M. G. Kenney, Shili Duan, Suman Shrestha, Dominic D. G. Owens, Matthew E. R. Maitland, Ailing Pon, Magdalena M. Szewczyk, Anthony Joseph Lamberto, Michael Menes, Fengling Li, Linda Z. Penn, Dalia Baršytė-Lovejoy, Nicholas G. Brown, Anthony M. Barsotti, Andrew W. Stamford, Jon L. Collins, Derek J. Wilson, Brian Raught, Jonathan D. Licht, Lindsey I. James, C.H. Arrowsmith

2024Nature Chemical Biology57 citationsDOIOpen Access PDF

Topics & Concepts

CullinUbiquitin ligaseUbiquitinMethyltransferaseEpigeneticsProtein degradationBiologyChemistryHistoneMutationCell biologyGeneticsBiochemistryCancer researchMethylationDNAGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
Recruitment of FBXO22 for targeted degradation of NSD2 | Litcius