Preclinical safety assessment of red emissive gold nanocluster conjugated crumpled MXene nanosheets: a dynamic duo for image-guided photothermal therapy
Barkha Singh, Rohan Bahadur, Priyanka Maske, Mayuri Gandhi, Dipty Singh, Rohit Srivastava
Abstract
dose), and toxicity was evaluated using various measures including body weight, hematology, serum biochemistry, and H&E staining. The findings from these studies suggest that the MXene gold nanoconjugate could be useful in a range of biomedical applications, with no observed toxicity following either oral or intravenous administration.
Topics & Concepts
Photothermal therapyNanoclustersIn vivoIn vitroMaterials scienceNanomaterialsToxicityFluorescenceNanotechnologyBiophysicsConjugated systemChemistryPolymerBiochemistryOrganic chemistryBiologyQuantum mechanicsPhysicsBiotechnologyComposite materialMXene and MAX Phase MaterialsGraphene and Nanomaterials ApplicationsNanocluster Synthesis and Applications