Concomitant metastatic head-and-neck cancer and pancreatic cancer assessed by αvβ6-integrin PET/CT using 68Ga-Trivehexin: incidental detection of a brain metastasis
J Rehm, Robert Winzer, Johannes Notni, Sebastian Hempel, Marius Distler, Gunnar Folprecht, Jörg Kotzerke
Abstract
68 Ga-Trivehexin is an investigative PET radiopharmaceutical targeting the "cancer integrin" v6, a tumor cell biomarker which is highly expressed by various carcinomas [1].Feasibility of targeting v6-integrin for cancer imaging has been demonstrated in preclinical and first clinical
Topics & Concepts
MedicineConcomitantHead and neck cancerMetastasisPancreatic cancerRadiologyHead and neckBrain metastasisCancerNuclear medicineOncologyInternal medicineSurgeryRadiopharmaceutical Chemistry and ApplicationsCell Adhesion Molecules ResearchPeptidase Inhibition and Analysis