3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
Zhiqiang Wang, Helen P. McWilliams-Koeppen, Hernan Reza, Julie R. Ostberg, Wuyang Chen, Xiuli Wang, Christian Huynh, Vibhuti Vyas, Wen-Chung Chang, Renate Starr, Jamie R. Wagner, Brenda Aguilar, Xin Yang, Xiwei Wu, Jinhui Wang, Wei Chen, Ellery Koelker-Wolfe, Christopher S. Seet, Amélie Montel‐Hagen, Gay M. Crooks, Stephen J. Forman, Christine E. Brown
Topics & Concepts
Induced pluripotent stem cellChimeric antigen receptorBiologyCD19Cell biologyclone (Java method)AntigenT cellImmunologyCancer researchImmune systemGeneticsGeneEmbryonic stem cellCAR-T cell therapy researchNanowire Synthesis and ApplicationsSilicon Carbide Semiconductor Technologies