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Inability of ovarian cancers to upregulate their MHC-class I surface expression marks their aggressiveness and increased susceptibility to NK cell-mediated cytotoxicity

Nishant Chovatiya, Kawaljit Kaur, Sara Huerta‐Yépez, Po-Chun Chen, Adam Neal, Gabriella DiBernardo, Serhat Gumrukcu, Sanaz Memarzadeh, Anahid Jewett

2022Cancer Immunology Immunotherapy23 citationsDOIOpen Access PDF

Topics & Concepts

CytotoxicityMHC class ICellCell cultureCancer researchMajor histocompatibility complexBiologyChemistryImmunologyAntigenIn vitroBiochemistryGeneticsImmune Cell Function and InteractionReproductive System and PregnancyT-cell and B-cell Immunology
Inability of ovarian cancers to upregulate their MHC-class I surface expression marks their aggressiveness and increased susceptibility to NK cell-mediated cytotoxicity | Litcius