Microfluidic-based modulation of triplet exciton decay in organic phosphorescent nanoparticles for size-assisted photodynamic antibacterial therapy
Cong Chao, Lingling Kang, Wenbo Dai, Changsheng Zhao, Jianbing Shi, Bin Tong, Zhengxu Cai, Yuping Dong
Abstract
M). BP/BQD nanoparticles below 300 nm show size-assisted antibacterial activity, demonstrated using a newly developed biophysical model. This novel microfluidic platform provides an efficient approach to convert host-guest RTP materials into photodynamic antibacterial agents and to promote the development of antibacterial agents without cytotoxicity and drug-resistance issues based on the host-guest RTP systems.
Topics & Concepts
PhosphorescenceMaterials scienceNanoparticleExcitonPhotodynamic therapyPhotochemistryNanotechnologyModulation (music)OptoelectronicsChemistryOpticsOrganic chemistryFluorescencePhysicsQuantum mechanicsAcousticsAdvanced biosensing and bioanalysis techniquesLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranostics