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Kaempferol improves depression-like behaviors through shifting microglia polarization and suppressing NLRP3 via tilting the balance of PPARγ and STAT1 signaling

Paul Su, Liming Liu, Yuhang Gong, Shuaijun Peng, Xiangli Yan, Ming Bai, Erping Xu, Yucheng Li

2024International Immunopharmacology21 citationsDOI

Topics & Concepts

MicrogliaPeroxisome proliferator-activated receptorKaempferolSignal transductionBalance (ability)ChemistryMedicineCancer researchReceptorBiologyInternal medicineNeuroscienceFlavonoidBiochemistryInflammationAntioxidantTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsGut microbiota and health
Kaempferol improves depression-like behaviors through shifting microglia polarization and suppressing NLRP3 via tilting the balance of PPARγ and STAT1 signaling | Litcius