Simple and versatile in situ thermo-sensitive hydrogel for rectal administration of SZ-A to alleviate inflammation and repair mucosal barrier in ulcerative colitis
Yan Yu, Jiawei Song, Dongdong Liu, Zihan Liu, Jialing Cheng, Zhiyang Chen, Yanfang Yang, Weizhe Jiang, Hongliang Wang, Jun Ye, Yuling Liu, Jun Ye, Yuling Liu
Topics & Concepts
Ulcerative colitisInflammationDrug deliverySelf-healing hydrogelsTumor necrosis factor alphaInflammatory bowel diseaseColitisMedicineRectal administrationBarrier functionTransforming growth factorPoloxamerPharmacologyGastroenterologyChemistryInternal medicineDiseaseBiologyPolymerPolymer chemistryCopolymerCell biologyOrganic chemistryInflammatory Bowel DiseaseGut microbiota and healthGastrointestinal motility and disorders