Enhanced trans-cleavage activity using CRISPR-Cas12a variant designed to reduce steric inhibition by cis-cleavage products
Injoo Hwang, Yo Han Song, Sang-Hwa Lee
Topics & Concepts
CRISPRCleavage (geology)Steric effectsChemistryCombinatorial chemistryStereochemistryBiochemistryBiologyGenePaleontologyFracture (geology)CRISPR and Genetic EngineeringGenetics, Aging, and Longevity in Model OrganismsMosquito-borne diseases and control